Breast cancer occurring in the mammary gland of men is infrequent. It accounts for 0. However, Paget disease of the male nipple is extremely rare.
Paget disease of the breast Paget disease of the nipple is a rare cancer in the skin of the nipple or in the skin closely surrounding the nipple. About percent of breast cancers are Paget disease of the breast [ 23 ]. Paget disease of the breast occurs more often in men than in women [ ].
All people, whether male or female, are born with some breast cells and tissue. Even so, male breast cancer is very rare. Less than one percent of all breast cancer cases develop in men, and only one in a thousand men will ever be diagnosed with breast cancer.
Male breast cancer is a rare cancer that forms in the breast tissue of men. Though breast cancer is most commonly thought of as a disease that affects women, breast cancer does occur in men. Men diagnosed with male breast cancer at an early stage have a good chance for a cure. Treatment typically involves surgery to remove the breast tissue.
It accounts for less than 2 percent of all breast cancer cases, predominantly in women but with rare cases in men. Symptoms can be similar to eczema. Paget's disease.
The patient was a year-old man with change in nipple appearance, itching and redness, and a palpable breast mass. Skin biopsy was performed and showed epidermis invaded by Paget cells, characterized by hyperchromatic nuclei and abundant pale-staining cytoplasm. Computed tomography and mammary ultrasonography confirmed the absence of an underlying invasive carcinoma, and the patient underwent right mastectomy and sentinel lymph node biopsy SLNB.
The most common initial symptom was ulceration and excoriation, while a breast mass was palpable in the majority of patients. Nipple changes were surprisingly rare, in contrast to the female. The prognosis of the disease in the male appears to be worse than in the female, with the Paget carcinoma carrying a worse prognosis than the "ordinary" male breast cancer.
Furthermore, MPD with invasion downward into the dermis of the male nipple has been reported rarely. A year-old Japanese man presented with a lump and eczema in the right nipple—areola area. Ultrasonography revealed only a cystic lesion below the right areola. With a diagnosis of MPD with invasion into the dermis associated with ductal carcinoma in situmastectomy and sentinel lymph node biopsy were performed.
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Paget's disease is an eczematous skin change of the nipple that is usually associated with an underlying breast malignancy. We present the case of a year-old Caucasian man with lymphomatoid papulosis who was diagnosed with Paget's disease of the nipple and who was treated successfully with surgery alone. We discuss the presentation, investigations, management and pathogenesis of Paget's disease of the nipple. The case highlights the need to be vigilant when new skin lesions arise in the context of an underlying chronic skin disorder.